Cialis may now be part of a cure for brain tumors
There are times when science seems a wonderful thing. There are cures for diseases and greater safety for people in their everyday lives. Equally, science seems to get involved in politics when it suggests the climate is changing or the oil is running out. Everyone wants to hear about the first. No-one wants to hear their lives may be forced to change. This month has seen the explosion of the drilling rig Horizon off the shore of Louisiana. This has forced the limits of science back into the headlines. Deep sea exploration always pushes limits on safety. Operating in deep water with robots may look good when Hollywood makes the movies, but it's less impressive when oil companies try to stop a break in the well caused by an explosion. Now, with thousands of gallons of oil a day leaking into the Gulf of Mexico, we could perhaps do with news of a better use of science. So here comes some research offering hope to those diagnosed with brain tumors.
Erectile dysfunction drugs are all phosphodiesterase 5 (PDE5) inhibitors. PDE5 is one of the set of PDE enzymes that regulates different parts of the body. In theory, the erectile dysfunction drugs are specific to PDE5 which controls the way in which the smooth muscles in the arteries leading into the penis dilate and contract. In fact, people can find these drugs affect other parts of the body where a different PDE enzyme is supposed to be exclusively in control. This is exploited with the development of the drugs to treat the arteries in the chest and lungs. This relieves a very painful condition called pulmonary arterial hypertension. In other words, scientists recognize that once a drug is loose in your body, the blood stream carries it everywhere.
For the most part, drug action is limited to the body by what is called the blood-brain barrier. This is a safety system designed to keep the blood and the fluid in the spine and brain from mixing. It prevents the brain from being infected by the majority of bacteria. Unfortunately, it also prevents the majority of drugs from passing through so treatments of diseases and disorders affecting the brain are not treatable with the usual range of medication. Scientists have now discovered the erectile dysfunction drugs encourage the barrier to permit limited mixing between the cerebral fluid and some chemicals in the blood.
This month sees the publication of new research combining the erectile dysfunction drugs with a drug targeting cancer cells. This drug works in the same way as antibodies and attacks tumor cells. It's now confirmed that the combination of drugs allows treatment of brain tumors and survival rates have been increased by 20%. This is the kind of science that always gets applause. When cialis came on to the market, men marvelled that a pill could produce relief for up to thirty-six hours. Now the reality that the same basic chemistry can also support the treatment of brain tumors is cheerful news. For otherwise healthy men, cialis will continue to offer support to sexual activity as needed. For men and women with tumors, we have the prospect of longer life combined with the continuing ability to think.